Gas Analysis in Fermentation Control
Gas analysis plays a crucial role in fermentation control by offering real-time data on key metabolic gases, allowing for precise adjustments throughout the process. Oxygen (O₂) and carbon dioxide (CO₂) levels serve as vital indicators of microbial or cell activity, reflecting growth phases, respiration rates, and overall process health. By continuously monitoring these gases, operators can fine-tune aeration rates, adjust nutrient supply, and detect deviations that could indicate contamination or suboptimal conditions. This level of control is particularly important in industries such as pharmaceuticals and biotechnology, where consistency and purity are paramount, as well as in food and beverage production, where fermentation directly impacts flavor, texture, and quality.
real-time monitoring and optimization of fermentation processes
Process Insights plays a key role in fermentation control by providing advanced gas analysis solutions that enable real-time monitoring and optimization of fermentation processes. Their high-performance gas analyzers, such as mass spectrometers, deliver precise measurements of critical gases. These insights help manufacturers maintain optimal fermentation conditions, improve yields, and ensure product consistency across industries such as pharmaceuticals, biotechnology, and food and beverage production.
By integrating Process Insights’ gas analysis technologies into fermentation systems, operators can automate control strategies, reduce manual sampling, and minimize contamination risks. Their analyzers offer fast response times and high sensitivity, allowing for immediate adjustments to aeration rates, nutrient supply, and other key process parameters. Additionally, Process Insights supports compliance with regulatory standards by providing accurate and reliable gas monitoring solutions, helping manufacturers enhance efficiency, reduce waste, and achieve sustainable production goals.
Our MGA 1200CS™ Fixed Magnet Mass Spectrometer is ideal for Microbial Fermentation & Mammalian Cell Culture analysis. The MGA 1200CS is capable of monitoring multiple fermenters and/or bioreactors with a single analyzer (up to 99).
- Precise measurement of RQ during both growth and productive phases of microbial fermentation
- Ensures viable cell density is achieved prior to transition to productive phase
- Precise measurement of RQ during both growth and productive phases of microbial fermentation
- Ensures viable cell density is achieved prior to transition to productive phase
- Monitor important indicators of limiting conditions
- Report DO2 probe drift c/o oxygen mass transfer (Kla)
- Seamlessly perform Effluent Gas Analysis for: Nitrogen %, Oxygen %, Argon %, CO2 %, and Derived Values (RQ, CER, OUR)
Optimizing Microbial Fermentation & Mammalian Cell Culture
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Why Choose the Process Insights MGA 1200CS?
The MGA 1200CS is a cutting-edge solution for gas analysis in fermentation control, offering high-precision, real-time monitoring of key process gases. Designed for industrial and laboratory applications, the MGA 1200CS ensures exceptional accuracy and reliability, helping operators optimize fermentation conditions with confidence. Equipped with advanced infrared (IR) and paramagnetic sensors, it delivers precise measurements of CO₂ and O₂, enabling real-time process adjustments that enhance efficiency and yield.
In addition to its analytical performance, the MGA 1200CS is engineered for ease of integration into existing fermentation systems. Its robust design ensures long-term durability in demanding environments, while its low-maintenance operation minimizes downtime and operational costs. Whether used in pharmaceutical bioprocessing, ethanol production, or food fermentation, the MGA 1200CS provides the data-driven insights needed to enhance process control, improve batch consistency, and drive operational excellence.
Our MGA 1200CS is state-of-the-art in process mass spectrometry with the first CyberSecure PLC enabled mass spectrometer. This process mass spectrometer is a fixed magnetic sector analyzer that provides rapid, accurate and stable real-time analysis of up to 16 gas components in multiple gas streams. It’s the fastest process mass spec on the market. With the ability to interface to process streams with capability of driving both rotary and solenoid manifolds, it delivers unmatched stability provides best-in industry drift specification and longest intervals for calibration. Only one single analyzer to calibrate and maintain.
MAX300-BIO™
One MAX300-BIO Bioreactor & Fermentation Quadrupole Mass Spectrometer is capable of analyzing up to 80 samples with the use of a single FAST multi-port valve. Accurate off-gas analysis tells the control loop exactly what is happening inside each reactor without the risks involved with probes or manual sampling.
The MAX300-BIO is a powerful analytical instrument designed for monitoring the gases produced and consumed during biological fermentation processes. Here are some of the benefits:
- Accurate and Reliable: Provides accurate and reliable measurements of gas concentrations, ensuring the optimization of bioreactor performance.
- Real-Time Monitoring: Provides real-time monitoring of gas concentrations, allowing for quick adjustments to bioreactor conditions.
- Easy to Use: Easy to use, with an intuitive interface and simple calibration procedure.
- Low Maintenance: Requires minimal maintenance, reducing downtime and maintenance costs.
- Multiple Gas Detection: Capable of detecting multiple gases simultaneously, including CO2, O2, H2, and CH4, making it a versatile option for bioreactor monitoring.
- Comprehensive Data Analysis: Includes data analysis software, allowing for comprehensive data analysis and visualization.
- Enhanced Bioreactor Performance: Enables the optimization of bioreactor performance, leading to increased yields and improved product quality.