Gas Analysis in Cell Culture | MONITOR GASES IN BIOREACTORS
Our cell culture gas analysis solutions provide real-time insights into O₂, CO₂, and other key parameters—ensuring optimal cell growth, productivity, and process control. Maintaining optimal conditions in these environments is essential to ensuring cell viability, growth, productivity, and the quality of the end product. Among the many variables that must be tightly controlled, gas composition — particularly levels of oxygen (O₂), carbon dioxide (CO₂), and other trace gases — is one of the most important.
That’s where advanced gas analyzers come in. Real-time monitoring of gases in bioreactors and incubators allows for precise control of the cellular microenvironment, ensuring that critical parameters remain within ideal ranges. Oxygen is essential for aerobic respiration and energy production, while CO₂ is often used to regulate pH levels in bicarbonate-buffered systems. Even slight fluctuations can impact cell metabolism, growth rates, and protein expression, making accurate gas measurement indispensable.
Our MGA 1200CS™ Fixed Magnetic Mass Spectrometer is ideal for Microbial Fermentation and Mammalian Cell Culture analysis. The MGA 1200CS is capable of monitoring multiple fermenters and/or bioreactors with a single analyzer (up to 99).
- Precise measurement of RQ during both growth and productive phases of microbial fermentation
- Ensures viable cell density is achieved prior to transition to productive phase
- Precise measurement of RQ during both growth and productive phases of microbial fermentation
- Ensures viable cell density is achieved prior to transition to productive phase
- Monitor important indicators of limiting conditions
- Report DO2 probe drift c/o oxygen mass transfer (Kla)
- Seamlessly perform Effluent Gas Analysis for: Nitrogen %, Oxygen %, Argon %, CO2 %, and Derived Values (RQ, CER, OUR)
Real-Time Gas Analysis Solutions for Cell Culture Applications
In cell culture and bioprocessing, maintaining the right gas environment is critical to ensure cell viability, metabolic activity, and consistent product quality. The MGA 1200CS Fixed Magnetic Mass Spectrometer offers a powerful solution for real-time, multi-component gas analysis in these sensitive applications. Learn more about our gas analysis solutions for cell culture – contact us!
Key Benefits in Cell Culture Applications
✅ Continuous Monitoring of O₂, CO₂, N₂, and other gases — Essential for maintaining optimal cellular respiration and pH balance.
✅ Fast Response Time — Allows for immediate detection of process shifts and quicker corrective actions.
✅ High Sensitivity & Stability — Capable of detecting trace-level changes, ideal for critical bioprocess parameters.
✅ Supports Closed-Loop Control — Enables integration with process control systems for automated gas regulation.
✅ Non-Invasive, Inline Analysis — Reduces contamination risks and sample handling errors.
Optimizing Microbial Fermentation & Mammalian Cell Culture
SALES | TRAINING INQUIRIES
AMERICAS: info.americas@process-insights.com
EMEAI (includes India): info.emeai@process-insights.com
APAC: info.apac@process-insights.com
CHINA: info.cn@process-insights.com
MGA 1200CS: Advanced Gas Analysis Solution for Fermentation Control
The MGA 1200CS is a state-of-the-art gas analysis solution designed specifically for fermentation control in industrial and laboratory environments. Delivering high-precision, real-time monitoring of critical gases like CO₂ and O₂, the MGA 1200CS empowers bioprocess operators to optimize fermentation conditions with unmatched accuracy and reliability.
Equipped with advanced infrared (IR) and paramagnetic sensors, this analyzer ensures precise measurement and rapid response, enabling real-time process adjustments that improve yield, enhance batch consistency, and reduce waste. Whether in pharmaceutical bioprocessing, ethanol production, or food and beverage fermentation, the MGA 1200CS provides the data needed for smarter, more efficient fermentation management.
High-Performance Mass Spectrometry for Process Gas Analysis
At the core of the MGA 1200CS is a fixed magnetic sector mass spectrometer, engineered for fast, stable, and accurate multi-gas analysis. It’s the fastest process mass spectrometer on the market, capable of analyzing up to 16 gas components across multiple gas streams—ideal for complex bioprocess environments.
The MGA 1200CS is also the first CyberSecure PLC-enabled mass spectrometer, delivering enhanced data security and seamless integration with modern control systems. Designed to interface easily with both rotary and solenoid valve manifolds, it features industry-leading drift performance and extended calibration intervals, meaning lower maintenance, reduced downtime, and higher operational efficiency.
Engineered for Integration and Reliability
Built for durability in demanding environments, the MGA 1200CS integrates easily into existing fermentation gas analysis systems. Its robust design and low-maintenance operation make it a reliable choice for long-term use, helping facilities improve process control, maintain regulatory compliance, and achieve consistent product quality.