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Hydrogen Peroxide Vapor Analyzer System for Real-Time VHP & HPV Sterilization Monitoring

Hydrogen Peroxide Vapor Analyzer System for Real-Time VHP & HPV Sterilization Monitoring

The ClearView® db Hydrogen Peroxide Vapor Analyzer System delivers continuous, real-time monitoring of Vaporized Hydrogen Peroxide (VHP®) and Hydrogen Peroxide Vapor (HPV) during sterilization and bio-decontamination processes. Designed for pharmaceutical manufacturing, biotechnology, medical devices, hospitals, and life science applications, the analyzer simultaneously measures hydrogen peroxide (H₂O₂) and water vapor (H₂O) to provide complete visibility into every sterilization cycle.

Using advanced near-infrared (NIR) spectroscopy, the ClearView db enables accurate monitoring without consumables or routine sensor replacement, helping manufacturers optimize cycle development, improve process control, reduce sterilization time, and support regulatory compliance.  Contact us today!

Simultaneous Hydrogen Peroxide & Moisture Measurement

Accurate sterilization depends on both hydrogen peroxide concentration and humidity.

The ClearView db continuously measures:

  • Hydrogen Peroxide Vapor (H₂O₂)
  • Water Vapor (H₂O)

This dual measurement enables operators to:

  • Optimize VHP injection
  • Improve condensation control
  • Shorten aeration cycles
  • Improve cycle repeatability
  • Reduce hydrogen peroxide consumption
  • Improve sterilization effectiveness

Applications

Pharmaceutical Manufacturing

Monitor sterilization cycles for:

  • Isolators
  • Aseptic filling lines
  • Barrier systems
  • RABS
  • Lyophilizers
  • Transfer chambers

Biotechnology

Support sterilization of:

  • Cell culture facilities
  • Vaccine production
  • Bioprocess equipment
  • Laboratory cleanrooms

Hospitals & Healthcare

Monitor VHP bio-decontamination for:

  • Operating rooms
  • Isolation rooms
  • Biological safety cabinets
  • Laboratory decontamination

Medical Device Manufacturing

Validate sterilization of:

  • Packaging lines
  • Assembly areas
  • Medical device production
  • Sterile manufacturing environments

Research Laboratories

Optimize sterilization processes for:

  • Pharmaceutical R&D
  • University laboratories
  • Biosafety laboratories
  • Animal research facilities

Optimize VHP Sterilization Cycles

Continuous monitoring allows operators to optimize every stage of the sterilization process.

Conditioning

Verify environmental conditions before hydrogen peroxide injection.

Injection

Monitor hydrogen peroxide concentration in real time.

Dwell

Maintain target sterilization concentration throughout exposure.

Aeration

Monitor peroxide removal to reduce downtime while ensuring operator safety.

Benefits of Real-Time Hydrogen Peroxide Vapor Monitoring

Continuous monitoring provides:

  • Faster cycle qualification
  • Reduced sterilization cycle times
  • Improved process consistency
  • Better product quality
  • Reduced hydrogen peroxide usage
  • Lower operating costs
  • Increased equipment availability
  • Simplified validation
  • Better regulatory documentation
Hydrogen Peroxide Vapor Sterilization Monitoring
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Easy Operation and Control

The ClearView db® H2O2 Vaporized Hydrogen Peroxide Sterilization Monitoring Solution is controlled via its touch screen or remotely via Ethernet (Modbus TCP/IP). All of the analytical calculations are encoded in the software.   The complete system consists of a ClearView Analyzer, one or two G-SST probes, and a pair of fiber optic cables for each probe. The analyzer is pre-calibrated at the factory. No programming is required by the user. Start-up requires powering the analyzer, connecting the probe or probes via the fiber optic cables, taking a ZERO reading in the dehumidified isolator and the H2O2 and H2O concentration measurements may begin.

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ANALYZER OPTIONAL ENCLOSURES

Typically for medical, pharmaceutical and food industries, the ClearView db® H2O2 Vaporized Hydrogen Peroxide Sterilization Monitoring Solution may be housed in a stainless-steel enclosure. Other enclosure options are available, such as, painted carbon steel, explosion-proof or purged depending on area classification requirements.

USER PROGRAMMABLE FEATURES

• Password protection for configuration changes
• Sampling time: 1 second minimum. User settable
• Reporting units: mg/L or ppm-V

ANALYZER SYSTEM ACCESSORIES AND OPTIONS

  • 2nd channel for additional independent sampling point
  • Custom length fiber cables
  • KF or Tri-clover® flanged fiber feed throughs and dual fiber feed throughs
  • Annual factory calibration service available
  • Universal power supply (110-240 VAC converter to 24 VDC)
  • Custom calibration for elevated temperature on request

FIBER CABLE

• 500 µm Ultra Low-OH fiber with stainless steel SMA-905 connectors
• Kevlar® protected or armored cables available

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VHP HYDROGEN PEROXIDE SOLUTION

OUR NIR-UV-VIS PROCESS AND LAB ANALYZER SPECTROMETER SOLUTIONS

NIR-O™

GUIDED WAVE™ Full Spectrum Near-Infrared (NIR) Process Analyzer
Process Insights_guided wave- NIR-O_process analyzer_GUIDED WAVE NIR UV-VIS process and lab analyzer spectrometers

LAB NIR-O™

GUIDED WAVE™ Full Spectrum Near-Infrared (NIR) Lab Analyzer
Process Insights_guided wave - Lab-NIR-O_analyzer_GUIDED WAVE NIR UV-VIS process and lab analyzer spectrometers

508 UV-VIS™ PROCESS ANALYZER

GUIDED WAVE™ UV-VIS Full Spectrum Process Analyzer
Process Insights_guided wave-M508-analyzer_analyzer_GUIDED WAVE NIR UV-VIS process and lab analyzer spectrometers

LAB 508 UV-VIS™ Benchtop

GUIDED WAVE™ UV-VIS Full Spectrum Benchtop Analyzer
Process Insights_Guided Wave_Model 508plus benchtop_analyzer_GUIDED WAVE NIR UV-VIS process and lab analyzer spectrometers

ClearView® db Dual Beam Photometer

GUIDED WAVE™ VIS-NIR Dual-Beam Photometer
Process Insights_Guided Wave ClearView-db_analyzer_GUIDED WAVE NIR UV-VIS process and lab analyzer spectrometers

ClearView® db Hydrogen Peroxide Vapor Analyzer System

GUIDED WAVE™ Hydrogen Peroxide Vapor Monitor
Process Insights_Guided Wave Hydrogen Peroxide Vapor Analyzer HPVA Photometer Systems

APHA/Platinum-Cobalt Color Analyzer System

GUIDED WAVE™ Complete Analytical System for Measuring APHA Color (Platinum-Cobalt ASTM D1209)
Process Insights_Guided Wave ClearView-db-enclosures-400x135

ASTM Color Analyzer System

GUIDED WAVE™ Complete Analytical System for Measuring ASTM Color (ASTM D1500, ASTM D1524)
Process Insights_Guided Wave ClearView-db-enclosures-400x135

Saybolt Color Analyzer System

GUIDED WAVE™ Complete Analytical System for Measuring Saybolt Color (ASTM D156, ASTM D604)
Process Insights_Guided Wave ClearView-db-enclosures-400x135

Turbidity Analyzer System

GUIDED WAVE™ VIS-NIR Dual-Beam Photometer

Probes & Flow Cells / Fiber & Accessories

GUIDED WAVE™ Accessories for NIR-UV-VIS & FT-NIR Analyzers
Process Insights_Probes & Flow Cells

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applications for our technologies

Aerospace & Government

agriculture

Agriculture

agriculture

Ammonia & Methanol

APHA COLOR MONITORING

APHA Color Monitoring

Atmospheric & Air Quality

Atmospheric & Air Quality

Battery Manufacturing

Battery Manufacturing

Biofuel Analysis

Biofuel Analysis

cell culture

Cell Culture

Chemical Manufacturing

Chemical Manufacturing

Carbon Capture

Carbon Capture

EMISSIONS MONITORING

Emissions Monitoring

Energy

Energy

Environmental Monitoring

Environmental Monitoring

Ethylene Oxide

Ethylene Oxide

fermentation control

Fermentation Control

Flare Gas Monitoring

Flare Gas Monitoring

Food & Beverage

Food & Beverage

Fuel Blending

Fuel Blending

Fuel Gas

Fuel Gas

Hydrogen Isotope & Helium Deuterium

Hydrogen Isotope & Helium Deuterium

Hydrogen Peroxide Sterilization Solution

Hydrogen Peroxide Sterilization Solution

Hydrogen Production

Hydrogen Production

Optical Absorption Spectroscopy

Optical Absorption Spectroscopy

Petrochemical & Refining

Petrochemical & Refining

Life Sciences

Life Sciences

Research Labs

Research Labs

Semiconductor

Semiconductor

Energy

Water Steam Cycle

BOD Water Analysis

BOD Water Analysis

COD Water Analysis

COD Water Analysis

TN Water Analysis

TN Water Analysis

TOC Water Analysis

TOC Water Analysis

Process Water

Process Water

Pure Water

Pure Water

Surface & Groundwater

Surface & Groundwater

Ultra-Pure Water

Ultra-Pure Water

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