The MGA 1200CS™ is an advanced bioprocess gas analyzer engineered for real-time fermentation monitoring, cell culture monitoring, and bioreactor off-gas analysis. Unlike conventional CO₂/O₂ analyzers, the MGA 1200CS uses a fixed magnetic sector mass spectrometer to simultaneously analyze up to 16 gas components while automatically calculating Oxygen Uptake Rate (OUR), Carbon Dioxide Evolution Rate (CER), and Respiratory Quotient (RQ).
Designed for laboratory research, pilot plants, and commercial biomanufacturing, the MGA 1200CS delivers continuous process intelligence that improves yield, shortens development time, and supports Process Analytical Technology (PAT), Quality by Design (QbD), and automated process control.
Why Choose a Process Insights Process Mass Spectrometer?
Why Monitor Fermentation Off-Gas?
Real-time off-gas analysis provides direct insight into metabolic activity inside fermenters and bioreactors.
Continuous gas monitoring enables operators to:
- Optimize microbial fermentation
- Improve mammalian cell culture performance
- Detect metabolic changes immediately
- Optimize feeding strategies
- Increase product yields
- Reduce batch variability
- Improve scale-up success
- Support automated process control
- Eliminate delays associated with laboratory sampling
Why Choose the MGA 1200CS?
Unlike traditional off-gas analyzers that measure only oxygen and carbon dioxide, the MGA 1200CS simultaneously analyzes multiple gases while continuously calculating critical bioprocess parameters.
Key Benefits
- Continuous online off-gas analysis
- Simultaneous measurement of up to 16 gases
- Automatic OUR calculation
- Automatic CER calculation
- Automatic Respiratory Quotient (RQ)
- Analyze up to 100 bioreactors from one analyzer
- New analytical data every 3 seconds
- Low-flow sampling down to 20 cc/min
- Ideal for bioreactors as small as 250 mL
- Best-in-class drift performance
- Long calibration intervals
- CyberSecure PLC architecture
- Native IIoT connectivity
These features distinguish the MGA 1200CS from conventional bioprocess gas analyzers that typically monitor only CO₂ and O₂
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APPLICATIONS
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Ammonia Biotech/Pharmaceuticals Ethylene Oxide |
Ethylene Cracking Steel Processing |
INDUSTRIES
Our Fixed Magnetic Sector Mass Spectrometer MGA 1200CS is an advanced instrument used in the food and beverage industry to analyze the composition of various samples, including fermented products, brewing, and culture cells. Here are some ways in which the instrument is used in the industry:
- Fermentation monitoring: Used to analyze the volatile compounds produced by the microorganisms. This helps the industry to understand the fermentation process and optimize it to produce the desired products. For example, in the production of beer, the instrument can be used to monitor the concentration of different types of alcohols, esters, and acids that contribute to the flavor profile of the final product.
- Quality control: Used in the food and beverage industry to analyze the composition of raw materials, intermediates, and final products. This helps to ensure that the products meet the required standards and are of consistent quality. For example, in the production of wine, the instrument can be used to analyze the concentration of different types of phenolic compounds, which contribute to the color and taste of the wine.
- Research and development: The instrument is also used in the food and beverage industry for research and development purposes. By analyzing the composition of various samples, researchers can understand the complex chemistry involved in the production of food and beverage products. This information can be used to develop new products or improve existing ones.
BENEFITS
The hazardous area compliant HMI for the MGA 1200CS Mass Spectrometer Gas Analyzer provides full access to system configuration, real-time data, stored data, system status and diagnostics. The native ethernet control architecture provides industrial connectivity for SCADA, DCS, SIS and Data Historians.
- Superior stability, sensitivity, resolution and ruggedness
- Only one single analyzer to calibrate and maintain – reduces maintenance costs
- Rapid analysis time – multiple components in 1 second
- Rugged cybersecure communication options standard
- Hazardous area compatible touchscreen HMI provides configuration and interrogation without opening the door or requiring a PC
- Role-based access permission standard
- Non scanning ultra-fast parallel processing of spectra
- Non-scanning – simultaneous analysis from multiple Faraday detectors providing real-time analysis
- Measures up to 16 components from mid-ppm to 100% for as many as 100 sampling sites
- Optional validation assistance for 21 CFR Part 11 compliance
- Continuous and instantaneous analysis
- Analyze up to 128 streams, including both process and calibration gases, in user defined order
- Standard communications: RS-232 Serial, Modbus® RTU & TCP/IP
- Optional communications: Analog (0-10 Vdc, 4-20 mA), OPC®, Profibus
- Scalable sampling systems and calibration manifolds available